Effect of β-1,6-Glucan Inhibitors on the Invasion Process of Candida albicans: Potential Mechanism of Their In Vivo Efficacy

β-1,6-Glucan is a fungus-specific cell wall component that is essential for the retention of many cell wall proteins. We recently reported the discovery of a small molecule inhibitor of β-1,6-glucan biosynthesis in yeasts. In the course of our study of its derivatives, we found a unique feature in t...

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Bibliographic Details
Main Authors: Kitamura, Akihiro, Higuchi, Saito, Hata, Masato, Kawakami, Katsuhiro, Yoshida, Kumi, Namba, Kenji, Nakajima, Ryohei
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737848/
https://ncbi.nlm.nih.gov/pubmed/19596881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00435-09
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