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(15)N{(31)P} REDOR NMR Studies of the Binding of Phosphonate Reaction Intermediate Analogues to Saccharomyces cerevisiae Lumazine Synthase

Lumazine synthase catalyzes the reaction of 5-amino-6-D-ribitylamino-2,4(1H,3H)-pyrimidinedione (1) with (S)-3,4-dihydroxybutanone 4-phosphate (2) to afford 6,7-dimethyl-8-D-ribityllumazine (3), the immediate biosynthetic precursor of riboflavin. The overall reaction implies a series of intermediate...

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Dettagli Bibliografici
Autori principali: Yu, Tsyr-Yan, O'Connor, Robert D., Sivertsen, Astrid C., Chiauzzi, Colby, Poliks, Barbara, Fischer, Markus, Bacher, Adelbert, Haase, Ilka, Cushman, Mark, Schaefer, Jacob
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630582/
https://ncbi.nlm.nih.gov/pubmed/19117095
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