Rosiglitazone Abrogates Bleomycin-Induced Scleroderma and Blocks Profibrotic Responses Through Peroxisome Proliferator-Activated Receptor-γ

The nuclear hormone receptor, peroxisome proliferator-activated receptor (PPAR)-γ, originally identified as a key mediator of adipogenesis, is expressed widely and implicated in diverse biological responses. Both natural and synthetic agonists of PPAR-γ abrogated the stimulation of collagen synthesi...

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Autores principales: Wu, Minghua, Melichian, Denisa S., Chang, Eric, Warner-Blankenship, Matthew, Ghosh, Asish K., Varga, John
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2009
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630560/
https://ncbi.nlm.nih.gov/pubmed/19147827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080574
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