IL-17 contributes to CD4-mediated graft-versus-host disease

CD4(+) interleukin-17 (IL-17)(+) T cells (Th17 cells) have been implicated in allograft rejection of solid organs and several autoimmune diseases. However, the functional role of Th17 cells in the development of acute graft-versus-host disease (GVHD) has not been well-characterized. We detected sign...

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Main Authors: Kappel, Lucy W., Goldberg, Gabrielle L., King, Christopher G., Suh, David Y., Smith, Odette M., Ligh, Cassandra, Holland, Amanda M., Grubin, Jeremy, Mark, Nicholas M., Liu, Chen, Iwakura, Yoichiro, Heller, Glenn, van den Brink, Marcel R. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2009
Teme:
Transplantation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630280/
https://ncbi.nlm.nih.gov/pubmed/18931341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-172155
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