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Distinct mechanisms act in concert to mediate cell cycle arrest

In response to DNA damage, cells arrest at specific stages in the cell cycle. This arrest must fulfill at least 3 requirements: it must be activated promptly; it must be sustained as long as damage is present to prevent loss of genomic information; and after the arrest, cells must re-enter into the...

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Detalhes bibliográficos
Main Authors: Toettcher, Jared E., Loewer, Alexander, Ostheimer, Gerard J., Yaffe, Michael B., Tidor, Bruce, Lahav, Galit
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630102/
https://ncbi.nlm.nih.gov/pubmed/19139404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806196106
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