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Rapid determination of hydrogen positions and protonation states of diisopropyl fluorophosphatase by joint neutron and X-ray diffraction refinement

Hydrogen atoms constitute about half of all atoms in proteins and play a critical role in enzyme mechanisms and macromolecular and solvent structure. Hydrogen atom positions can readily be determined by neutron diffraction, and as such, neutron diffraction is an invaluable tool for elucidating molec...

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Bibliografski detalji
Glavni autori: Blum, Marc-Michael, Mustyakimov, Marat, Rüterjans, Heinz, Kehe, Kai, Schoenborn, Benno P., Langan, Paul, Chen, Julian C.-H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630072/
https://ncbi.nlm.nih.gov/pubmed/19136630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807842106
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