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X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): perdeuteration of proteins for neutron diffraction

The signal-to-noise ratio is one of the limiting factors in neutron macromolecular crystallography. Protein perdeuteration, which replaces all H atoms with deuterium, is a method of improving the signal-to-noise ratio of neutron crystallography experiments by reducing the incoherent scattering of th...

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Hlavní autoři: Blum, Marc-Michael, Tomanicek, Stephen J., John, Harald, Hanson, B. Leif, Rüterjans, Heinz, Schoenborn, Benno P., Langan, Paul, Chen, Julian C.-H.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852326/
https://ncbi.nlm.nih.gov/pubmed/20383004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110004318
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