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Neutron structure and mechanistic studies of diisopropyl fluorophosphatase (DFPase)

Diisopropyl fluorophosphatase (DFPase) is a calcium-dependent phosphotriesterase that acts on a variety of highly toxic organophosphorus compounds that act as inhibitors of acetylcholinesterase. The mechanism of DFPase has been probed using a variety of methods, including isotopic labelling, which d...

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Detalhes bibliográficos
Main Authors: Chen, Julian C.-H., Mustyakimov, Marat, Schoenborn, Benno P., Langan, Paul, Blum, Marc-Michael
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967418/
https://ncbi.nlm.nih.gov/pubmed/21041927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444910034013
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