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Aryl bis(Diazeniumdiolates): Potent Inducers of S-Glutathionylation of Cellular Proteins and Their in Vitro Anti-Proliferative Activities

A number of bis(diazeniumdiolates) that we designed to release up to four moles of nitric oxide (NO) and which are structural analogues of the NO prodrug and anti-cancer lead compound, O(2)-{2,4-dinitro-5-[4-(N-methylamino)benzoyloxy]phenyl} 1-(N,N-dimethylamino)diazen-1-ium-1,2- diolate (PABA/NO),...

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Bibliografische gegevens
Hoofdauteurs: Andrei, Daniela, Maciag, Anna E., Chakrapani, Harinath, Citro, Michael L., Keefer, Larry K., Saavedra, Joseph E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629944/
https://ncbi.nlm.nih.gov/pubmed/19053760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800831y
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