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Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation

BACKGROUND: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent results indicate that not only the presence of a motif but also motif context (for example the orientation of a motif or its...

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Detalhes bibliográficos
Main Authors: Westholm, Jakub Orzechowski, Xu, Feifei, Ronne, Hans, Komorowski, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629780/
https://ncbi.nlm.nih.gov/pubmed/19014636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-484
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