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Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation

BACKGROUND: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent results indicate that not only the presence of a motif but also motif context (for example the orientation of a motif or its...

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Main Authors: Westholm, Jakub Orzechowski, Xu, Feifei, Ronne, Hans, Komorowski, Jan
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629780/
https://ncbi.nlm.nih.gov/pubmed/19014636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-484
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