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Human Rad52-mediated homology search and annealing occurs by continuous interactions between overlapping nucleoprotein complexes

The Rad52 protein has critical functions in distinct pathways of the homology-directed DNA repair, one of which is to promote the annealing of complementary strands of DNA. Both yeast and human Rad52 proteins organize into ring-shaped oligomers with the predominant form being a heptamer. Despite the...

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Detalhes bibliográficos
Main Authors: Rothenberg, Eli, Grimme, Jill M., Spies, Maria, Ha, Taekjip
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629295/
https://ncbi.nlm.nih.gov/pubmed/19074292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810317106
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