Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

Normal cellular lifespan is contingent upon preserving outer mitochondrial membrane (OMM) integrity, as permeabilization promotes apoptosis. BCL-2 family proteins control mitochondrial outer membrane permeabilization (MOMP) by regulating the activation of the pro-apoptotic BCL-2 effector molecules,...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Chipuk, Jerry E., Fisher, John C., Dillon, Christopher P., Kriwacki, Richard W., Kuwana, Tomomi, Green, Douglas R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629294/
https://ncbi.nlm.nih.gov/pubmed/19074266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808036105
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller