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Fluorescence detection of the movement of single KcsA subunits reveals cooperativity

The prokaryotic KcsA channel is gated at the helical bundle crossing by intracellular protons and inactivates at the extracellular selectivity filter. The C-terminal transmembrane helix has to undergo a conformational change for potassium ions to access the central cavity. Whereas a partial opening...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Blunck, Rikard, McGuire, Hugo, Hyde, H. Clark, Bezanilla, Francisco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629256/
https://ncbi.nlm.nih.gov/pubmed/19074286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807056106
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