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Fluorescence detection of the movement of single KcsA subunits reveals cooperativity
The prokaryotic KcsA channel is gated at the helical bundle crossing by intracellular protons and inactivates at the extracellular selectivity filter. The C-terminal transmembrane helix has to undergo a conformational change for potassium ions to access the central cavity. Whereas a partial opening...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629256/ https://ncbi.nlm.nih.gov/pubmed/19074286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807056106 |
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