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Eomesodermin Requires Transforming Growth Factor-β/Activin Signaling and Binds Smad2 to Activate Mesodermal Genes
The T-box gene Eomesodermin (Eomes) is required for early embryonic mesoderm differentiation in mouse, frog (Xenopus laevis), and zebrafish, is important in late cardiac development in Xenopus, and for CD8(+) T effector cell function in mouse. Eomes can ectopically activate many mesodermal genes. Ho...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629102/ https://ncbi.nlm.nih.gov/pubmed/19036723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808704200 |
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