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Identification of 24p3 as a Direct Target of Foxo3a Regulated by Interleukin-3 through the Phosphoinositide 3-Kinase/Akt Pathway
Pro-apoptotic protein 24p3, a member of lipocalin family, is induced upon interleukin-3 (IL-3) deprivation and plays a pivotal role in induction of apoptosis in hematopoietic cells. However, the molecular mechanism by which IL-3 regulates 24p3 expression remains largely unknown. Here, we show that 2...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629101/ https://ncbi.nlm.nih.gov/pubmed/19056725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806131200 |
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