Src Phosphorylation of μ-Receptor Is Responsible for the Receptor Switching from an Inhibitory to a Stimulatory Signal

Recent studies have revealed that in G protein-coupled receptor signalings switching between G protein- and β-arrestin (βArr)-dependent pathways occurs. In the case of opioid receptors, the signal is switched from the initial inhibition of adenylyl cyclase (AC) to an increase in AC activity (AC acti...

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Bibliografiske detaljer
Main Authors: Zhang, Lei, Zhao, Hui, Qiu, Yu, Loh, Horace H., Law, Ping-Yee
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629085/
https://ncbi.nlm.nih.gov/pubmed/19029294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807971200
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