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Effects of small interfering RNA targeting thymidylate synthase on survival of ACC3 cells from salivary adenoid cystic carcinoma

BACKGROUND: Thymidylate synthase (TS) is an important target for chemotherapeutic treatment of cancer and high expression of TS has been associated with poor prognosis or refractory disease in several cancers including colorectal and head and neck cancer. Although TS is known to regulate cell cycles...

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Detalhes bibliográficos
Main Authors: Shirasaki, Takashi, Maruya, Shin-ichiro, Mizukami, Hiroki, Kakehata, Seiji, Kurotaki, Hidekachi, Yagihashi, Soroku, Shinkawa, Hideichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628925/
https://ncbi.nlm.nih.gov/pubmed/19036131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-348
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