Differential expression of topoisomerase IIα protein in salivary gland carcinomas: histogenetic and prognostic implications

BACKGROUND: Salivary gland carcinomas are relatively uncommon heterogeneous malignancies characterized by locoregional invasion and distant metastasis. Topoisomerase IIα (topoIIα), located at chromosome 17q21-22, is considered a major mediator of cell proliferation and DNA replication. The purpose o...

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Detalhes bibliográficos
Main Authors: Maruya, Shin-ichiro, Shirasaki, Takashi, Nagaki, Takahiko, Kakehata, Seiji, Kurotaki, Hidekachi, Mizukami, Hiroki, Shinkawa, Hideichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654461/
https://ncbi.nlm.nih.gov/pubmed/19250538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-72
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