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Effects of small interfering RNA targeting thymidylate synthase on survival of ACC3 cells from salivary adenoid cystic carcinoma

BACKGROUND: Thymidylate synthase (TS) is an important target for chemotherapeutic treatment of cancer and high expression of TS has been associated with poor prognosis or refractory disease in several cancers including colorectal and head and neck cancer. Although TS is known to regulate cell cycles...

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Autors principals: Shirasaki, Takashi, Maruya, Shin-ichiro, Mizukami, Hiroki, Kakehata, Seiji, Kurotaki, Hidekachi, Yagihashi, Soroku, Shinkawa, Hideichi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628925/
https://ncbi.nlm.nih.gov/pubmed/19036131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-348
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