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Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by L-DOPA treatment

Dysregulation of dopamine (DA) receptors is believed to underlie Parkinson’s disease pathology and L-DOPA-induced motor complications. DA receptors are subject to regulation by G protein-coupled receptor kinases (GRKs) and arrestins. DA lesion with 6-hydroxydopamine caused multiple protein- and brai...

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Autores principales: Ahmed, M. Rafiuddin, Bychkov, Evgeny, Gurevich, Vsevolod V., Benovic, Jeffrey L., Gurevich, Eugenia V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628845/
https://ncbi.nlm.nih.gov/pubmed/17996024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.05104.x
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