Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data

OBJECTIVE—This study examined how differences in the BMI distribution of type 2 diabetic case subjects affected genome-wide patterns of type 2 diabetes association and considered the implications for the etiological heterogeneity of type 2 diabetes. RESEARCH DESIGN AND METHODS—We reanalyzed data fro...

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Auteurs principaux: Timpson, Nicholas J., Lindgren, Cecilia M., Weedon, Michael N., Randall, Joshua, Ouwehand, Willem H., Strachan, David P., Rayner, N. William, Walker, Mark, Hitman, Graham A., Doney, Alex S.F., Palmer, Colin N.A., Morris, Andrew D., Hattersley, Andrew T., Zeggini, Eleftheria, Frayling, Timothy M., McCarthy, Mark I.
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2009
Sujets:
Genetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628627/
https://ncbi.nlm.nih.gov/pubmed/19056611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0906
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