Combining Information from Common Type 2 Diabetes Risk Polymorphisms Improves Disease Prediction

BACKGROUND: A limited number of studies have assessed the risk of common diseases when combining information from several predisposing polymorphisms. In most cases, individual polymorphisms only moderately increase risk (~20%), and they are thought to be unhelpful in assessing individuals' risk...

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Main Authors: Weedon, Michael N, McCarthy, Mark I, Hitman, Graham, Walker, Mark, Groves, Christopher J, Zeggini, Eleftheria, Rayner, N. William, Shields, Beverley, Owen, Katharine R, Hattersley, Andrew T, Frayling, Timothy M
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2006
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1584415/
https://ncbi.nlm.nih.gov/pubmed/17020404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030374
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