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Glucose and Pharmacological Modulators of ATP-Sensitive K(+) Channels Control [Ca(2+)](c) by Different Mechanisms in Isolated Mouse α-Cells
OBJECTIVE—We studied how glucose and ATP-sensitive K(+) (K(ATP)) channel modulators affect α-cell [Ca(2+)](c). RESEARCH DESIGN AND METHODS—GYY mice (expressing enhanced yellow fluorescent protein in α-cells) and NMRI mice were used. [Ca(2+)](c), the K(ATP) current (I(KATP), perforated mode) and cell...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Diabetes Association
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628615/ https://ncbi.nlm.nih.gov/pubmed/19008345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1298 |
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