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Tolbutamide stimulation of pancreatic β-cells involves both cell recruitment and increase in the individual Ca(2+) response
1. Individual pancreatic β-cells are functionally heterogeneous. Their sensitivity to glucose is variable, so that the proportion of active cells increases with the glucose concentration (recruitment). 2. We have investigated whether sulphonylureas also recruit β-cells, by measuring cytoplasmic Ca(2...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572813/ https://ncbi.nlm.nih.gov/pubmed/11399675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704108 |
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