Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system

Understanding the control of myelin formation by oligodendrocytes is essential for treating demyelinating diseases. Neuregulin-1 (NRG1) type III, an EGF-like growth factor, is essential for myelination in the PNS. It is thus thought that NRG1/ErbB signaling also regulates CNS myelination, a view sug...

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Autori principali: Brinkmann, B. G., Agarwal, A., Sereda, M. W., Garratt, A. N., Müller, T., Wende, H., Stassart, R. M., Nawaz, S., Humml, C., Velanac, V., Radyuschkin, K., Goebbels, S., Fischer, T. M., Franklin, R. J., Lai, C., Ehrenreich, H., Birchmeier, C., Schwab, M. H., Nave, K.-A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628490/
https://ncbi.nlm.nih.gov/pubmed/18760695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.06.028
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