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R93W mutation in Orai1 causes impaired calcium influx in platelets
The intracellular Ca(2+) concentration of many nonexcitable cells is regulated by calcium store release and store-operated calcium entry (SOCE). In platelets, STIM1 was recently identified as the main calcium sensor expressed in the endoplasmic reticulum. To evaluate the role of the SOC channel moie...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2628374/ https://ncbi.nlm.nih.gov/pubmed/18952890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-174516 |
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