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The 1.6 Å Crystal Structure of Mycobacterium smegmatis MshC: The Penultimate Enzyme in the Mycothiol Biosynthetic Pathway

Mycobacterium smegmatis MshC catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins, the penultimate step in mycothiol biosynthesis. Attempts to crystallize the native, full-length MshC have been unsuccessful. However, incubation of the enzyme with the cysteinyl a...

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Detaylı Bibliyografya
Asıl Yazarlar: Tremblay, L.W., Fan, F., Vetting, M.W., Blanchard, J.S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2628295/
https://ncbi.nlm.nih.gov/pubmed/19053270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801708f
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