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Short Telomeres Initiate Telomere Recombination in Primary and Tumor Cells
Human tumors that lack telomerase maintain telomeres by alternative lengthening mechanisms. Tumors can also form in telomerase-deficient mice; however, the genetic mechanism responsible for tumor growth without telomerase is unknown. In yeast, several different recombination pathways maintain telome...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2627939/ https://ncbi.nlm.nih.gov/pubmed/19180191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000357 |
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