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End Resection Initiates Genomic Instability in the Absence of Telomerase
Telomere dysfunction causes genomic instability. However, the mechanism that initiates this instability when telomeres become short is unclear. We measured the mutation rate and loss of heterozygosity along a chromosome arm in diploid yeast that lacked telomerase to distinguish between mechanisms fo...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC262688/ https://ncbi.nlm.nih.gov/pubmed/14612391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8450-8461.2003 |
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