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Template boundary definition in mammalian telomerase

Telomerase uses a short template sequence in its intrinsic RNA component to synthesize telomere repeats. Disruption of the helix P1b in human telomerase RNA or alteration of its distance from the template resulted in telomerase copyingresidues past the normal template boundary both in vivo and in vi...

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Detalles Bibliográficos
Main Authors: Chen, Jiunn-Liang, Greider, Carol W.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC280623/
https://ncbi.nlm.nih.gov/pubmed/14630939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1140303
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