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Origin of the sharp boundary that discriminates positive and negative selection of thymocytes
T lymphocytes play a key role in adaptive immunity and are activated by interactions of their T cell receptors (TCR) with peptides (p) derived from antigenic proteins bound to MHC gene products. The repertoire of T lymphocytes available in peripheral organs is tuned in the thymus. Immature T lymphoc...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626737/ https://ncbi.nlm.nih.gov/pubmed/19098101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805981105 |
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