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Increased Malignancy of Neu-Induced Mammary Tumors Overexpressing Active Transforming Growth Factor β1
To determine if Neu is dominant over transforming growth factor β (TGF-β), we crossed mouse mammary tumor virus (MMTV)-Neu mice with MMTV-TGF-β1(S223/225) mice expressing active TGF-β1 in the mammary gland. Bigenic (NT) and Neu-induced mammary tumors developed with a similar latency. The bigenic tum...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC262670/ https://ncbi.nlm.nih.gov/pubmed/14612410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.23.8691-8703.2003 |
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