F-spondin, a neuroregulatory protein, is up-regulated in osteoarthritis and regulates cartilage metabolism via TGF-β activation

In osteoarthritis (OA) articular chondrocytes undergo phenotypic changes culminating in the progressive loss of cartilage from the joint surface. The molecular mechanisms underlying these changes are poorly understood. Here we report enhanced (∼7-fold) expression of F-spondin, a neuronal extracellul...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Attur, Mukundan G., Palmer, Glyn D., Al-Mussawir, Hayf E., Dave, Mandar, Teixeira, Cristina C., Rifkin, Daniel B., Appleton, C. Thomas G., Beier, Frank, Abramson, Steven B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Federation of American Societies for Experimental Biology 2009
Θέματα:
Research Communications
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626615/
https://ncbi.nlm.nih.gov/pubmed/18780763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-114363
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