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Sequence-specific Retention and Regulated Integration of a Nascent Membrane Protein by the Endoplasmic Reticulum Sec61 Translocon

A defining feature of eukaryotic polytopic protein biogenesis involves integration, folding, and packing of hydrophobic transmembrane (TM) segments into the apolar environment of the lipid bilayer. In the endoplasmic reticulum, this process is facilitated by the Sec61 translocon. Here, we use a phot...

詳細記述

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書誌詳細
主要な著者: Pitonzo, David, Yang, Zhongying, Matsumura, Yoshihiro, Johnson, Arthur E., Skach, William R.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626564/
https://ncbi.nlm.nih.gov/pubmed/19019984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-09-0902
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