The m-AAA Protease Processes Cytochrome c Peroxidase Preferentially at the Inner Boundary Membrane of Mitochondria

Eitemau Tebyg

• Dislocation by the m-AAA Protease Increases the Threshold Hydrophobicity for Retention of Transmembrane Helices in the Inner Membrane of Yeast Mitochondria
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  Cyhoeddwyd: (2013)
• Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane
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• AAA proteases with catalytic sites on opposite membrane surfaces comprise a proteolytic system for the ATP-dependent degradation of inner membrane proteins in mitochondria.
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• m-AAA protease-driven membrane dislocation allows intramembrane cleavage by rhomboid in mitochondria
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