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Ras Signaling Influences Permissiveness of Malignant Peripheral Nerve Sheath Tumor Cells to Oncolytic Herpes

Lack of expression of neurofibromin in neurofibromatosis 1 and its lethal derivative, malignant peripheral nerve sheath tumors (MPNSTs), is thought to result in the overactivation of the Ras signaling pathway. Our previous studies have shown that cells with overactivation in the Ras pathway are more...

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Détails bibliographiques
Auteurs principaux: Farassati, Faris, Pan, Weihong, Yamoutpour, Farnaz, Henke, Susann, Piedra, Mark, Frahm, Silke, Al-Tawil, Said, Mangrum, Wells I., Parada, Luis F., Rabkin, Samuel D., Martuza, Robert L., Kurtz, Andreas
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626396/
https://ncbi.nlm.nih.gov/pubmed/18988803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.080376
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