Ral Overactivation in Malignant Peripheral Nerve Sheath Tumors

Ras leads an important signaling pathway that is deregulated in neurofibromatosis type 1 and malignant peripheral nerve sheath tumor (MPNST). In this study, we show that overactivation of Ras and many of its downstream effectors occurred in only a fraction of MPNST cell lines. RalA, however, was ove...

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Detalhes bibliográficos
Main Authors: Bodempudi, Vidya, Yamoutpoor, Farnaz, Pan, Weihong, Dudek, Arkadiusz Z., Esfandyari, Tuba, Piedra, Mark, Babovick-Vuksanovic, Dusica, Woo, Richard A., Mautner, Victor F., Kluwe, Lan, Clapp, D. Wade, De Vries, George H., Thomas, Stacey L., Kurtz, Andreas, Parada, Luis F., Farassati, Faris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704746/
https://ncbi.nlm.nih.gov/pubmed/19414599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01153-08
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