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Alternate (13)C-(12)C labeling for complete mainchain resonance assignments using Cα direct-detection with applicability towards fast relaxing protein systems
[Image: see text] Experiments that use direct (13)C detection and take advantage of the slower relaxation of (13)C magnetization compared to 1H offer an attractive strategy for extending the limits of NMR to include larger, highly dynamic, or paramagnetic proteins. Because carbonyl carbons ((13)C′)...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626166/ https://ncbi.nlm.nih.gov/pubmed/19049287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja806956p |
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