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Morphogenetic competence of HNF4α-deficient mouse hepatic cells

BACKGROUND/AIMS: To specify roles of HNF4α in mouse liver development, we have analyzed the ex vivo morphogenetic potential of HNF4α-null embryonic hepatic cells. METHODS: Using mice with floxed or deficiency alleles of HNF4α, hepatic cells lacking this transcription factor were explanted into prima...

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Detalhes bibliográficos
Main Authors: Hayhurst, Graham P., Strick-Marchand, Hélène, Mulet, Céline, Richard, Anne-Françoise, Morosan, Serban, Kremsdorf, Dina, Weiss, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2625285/
https://ncbi.nlm.nih.gov/pubmed/18617288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2008.04.024
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