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Bipotential mouse embryonic liver stem cell lines contribute to liver regeneration and differentiate as bile ducts and hepatocytes

Cell lines have many advantages: they can be manipulated genetically, expanded, and stockpiled for organ transplantation. Freshly isolated hepatocytes, oval cells, pancreatic cells, and hematopoietic stem cells have been shown to repopulate the damaged liver. Here we show that bipotential mouse embr...

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Main Authors: Strick-Marchand, Hélène, Morosan, Serban, Charneau, Pierre, Kremsdorf, Dina, Weiss, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC420399/
https://ncbi.nlm.nih.gov/pubmed/15155906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401092101
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