IκB Kinase-Independent IκBα Degradation Pathway: Functional NF-κB Activity and Implications for Cancer Therapy

Antiapoptotic activity of NF-κB in tumors contributes to acquisition of resistance to chemotherapy. Degradation of IκB is a seminal step in activation of NF-κB. The IκB kinases, IKK1 and IKK2, have been implicated in both IκB degradation and subsequent modifications of NFκB. Using mouse embryo fibro...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Mol Cell Biol
Huvudupphov:	Tergaonkar, Vinay, Bottero, Virginie, Ikawa, Masahito, Li, Qiutang, Verma, Inder M.
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Taylor & Francis 2003
Ämnen:	Cell Growth and Development
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585967/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8070-8083.2003
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!