Biochemical Characterization of the Ran-RanBP1-RanGAP System: Are RanBP Proteins and the Acidic Tail of RanGAP Required for the Ran-RanGAP GTPase Reaction?

RanBP type proteins have been reported to increase the catalytic efficiency of the RanGAP-mediated GTPase reaction on Ran. Since the structure of the Ran-RanBP1-RanGAP complex showed RanBP1 to be located away from the active site, we reinvestigated the reaction using fluorescence spectroscopy under...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Seewald, Michael J., Kraemer, Astrid, Farkasovsky, Marian, Körner, Carolin, Wittinghofer, Alfred, Vetter, Ingrid R.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2003
Matèries:	Cell Growth and Development
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8124-8136.2003
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