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Biochemical Characterization of the Ran-RanBP1-RanGAP System: Are RanBP Proteins and the Acidic Tail of RanGAP Required for the Ran-RanGAP GTPase Reaction?

RanBP type proteins have been reported to increase the catalytic efficiency of the RanGAP-mediated GTPase reaction on Ran. Since the structure of the Ran-RanBP1-RanGAP complex showed RanBP1 to be located away from the active site, we reinvestigated the reaction using fluorescence spectroscopy under...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Seewald, Michael J., Kraemer, Astrid, Farkasovsky, Marian, Körner, Carolin, Wittinghofer, Alfred, Vetter, Ingrid R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262373/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14585972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.22.8124-8136.2003
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