Gamma interferon activates human macrophages to become tumoricidal and leishmanicidal but enhances replication of macrophage-associated mycobacteria.

Recombinant human gamma interferon (rIFN-gamma) was examined for its ability to activate human peripheral blood monocyte-derived macrophages to kill tumor cells and to affect the replication of two phylogenetically distinct intracellular pathogens, Mycobacterium tuberculosis and Leishmania donovani....

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Main Authors: Douvas, G S, Looker, D L, Vatter, A E, Crowle, A J
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC262123/
https://ncbi.nlm.nih.gov/pubmed/3930401
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