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Gamma interferon activates human macrophages to become tumoricidal and leishmanicidal but enhances replication of macrophage-associated mycobacteria.

Recombinant human gamma interferon (rIFN-gamma) was examined for its ability to activate human peripheral blood monocyte-derived macrophages to kill tumor cells and to affect the replication of two phylogenetically distinct intracellular pathogens, Mycobacterium tuberculosis and Leishmania donovani....

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Douvas, G S, Looker, D L, Vatter, A E, Crowle, A J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1985
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262123/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3930401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.50.1.1-8.1985
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