Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic.

Mycobacterium tuberculosis and Mycobacterium avium multiply in cultured human macrophages (MP) within membrane-enclosed vesicles. These vesicles are generally assumed to be acidic. The evidence most frequently cited for this assumption is that pyrazinamide, which requires an acid pH to be effective,...

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Vydáno v:Infect Immun
Hlavní autoři: Crowle, A J, Dahl, R, Ross, E, May, M H
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1991
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257922/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1902198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.5.1823-1831.1991
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