Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic.

Mycobacterium tuberculosis and Mycobacterium avium multiply in cultured human macrophages (MP) within membrane-enclosed vesicles. These vesicles are generally assumed to be acidic. The evidence most frequently cited for this assumption is that pyrazinamide, which requires an acid pH to be effective,...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Crowle, A J, Dahl, R, Ross, E, May, M H
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1991
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257922/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1902198/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.5.1823-1831.1991
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