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Loss of the Mitochondrial Nucleoid Protein, Abf2p, Destabilizes Repetitive DNA in the Yeast Mitochondrial Genome

Loss of Abf2p, an abundant mitochondrial nucleoid-associated protein, results in increased mitochondrial frameshifts and direct-repeat mediated deletions but has no effect on the rate of mitochondrial point mutations. The instability of repeated sequences in this strain may be linked to the loss of...

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Bibliografske podrobnosti
Main Authors: Sia, Rey A., Carrol, Stephanie, Kalifa, Lidza, Hochmuth, Christine, Sia, Elaine A.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621183/
https://ncbi.nlm.nih.gov/pubmed/19015543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.095786
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