Mitochondrial Genome Maintenance: Roles for Nuclear Nonhomologous End-Joining Proteins in Saccharomyces cerevisiae

Mitochondrial DNA (mtDNA) deletions are associated with sporadic and inherited diseases and age-associated neurodegenerative disorders. Approximately 85% of mtDNA deletions identified in humans are flanked by short directly repeated sequences; however, mechanisms by which these deletions arise are u...

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Detaylı Bibliyografya
Asıl Yazarlar: Kalifa, Lidza, Quintana, Daniel F., Schiraldi, Laura K., Phadnis, Naina, Coles, Garry L., Sia, Rey A., Sia, Elaine A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2012
Konular:
Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296257/
https://ncbi.nlm.nih.gov/pubmed/22214610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.138214
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